loading...| Preferred Name | Doxapram Hydrochloride | |
| Synonyms |
3,3-Diphenyl-1-ethyl-4-(2-morpholinoethyl)-2-pyrrolidinone Hydrochloride Doxapram Hydrochloride 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone Monohydrochloride, Monohydrate DOXAPRAM HYDROCHLORIDE Dopram Stimulexin |
|
| Definitions |
A peripheral and central respiratory stimulant with a brief duration of action. Doxapram hydrochloride stimulates respiration by an action on chemoreceptors in the carotid arteries and, at increased dosage, stimulates central respiratory centers in the medulla as well as other parts of the brain and spinal cord. This results in an increased tidal volume and a slightly increased respiratory rate. Doxapram hydrochloride may also improve cardiac output probably due to an increased release of catecholamines. This respiratory stimulant is used in postanesthesia respiratory depression. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47500 |
|
| CAS_Registry |
7081-53-0 |
|
| CHEBI_ID |
CHEBI:31520 |
|
| Chemical_Formula |
C24H30N2O2.HCl.H2O |
|
| code |
C47500 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A peripheral and central respiratory stimulant with a brief duration of action. Doxapram hydrochloride stimulates respiration by an action on chemoreceptors in the carotid arteries and, at increased dosage, stimulates central respiratory centers in the medulla as well as other parts of the brain and spinal cord. This results in an increased tidal volume and a slightly increased respiratory rate. Doxapram hydrochloride may also improve cardiac output probably due to an increased release of catecholamines. This respiratory stimulant is used in postanesthesia respiratory depression. |
|
| FDA_UNII_Code |
P5RU6UOQ5Y |
|
| FULL_SYN |
3,3-Diphenyl-1-ethyl-4-(2-morpholinoethyl)-2-pyrrolidinone Hydrochloride Doxapram Hydrochloride 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone Monohydrochloride, Monohydrate DOXAPRAM HYDROCHLORIDE Dopram Stimulexin |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Doxapram Hydrochloride |
|
| Legacy Concept Name |
Doxapram_Hydrochloride |
|
| NSC Number |
170958 |
|
| Preferred_Name |
Doxapram Hydrochloride |
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| prefixIRI |
Thesaurus:C47500 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0282152 |
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| subClassOf |