National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Dexpanthenol
Synonyms

D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide

Dexpanthenol

Provitamin B5

DEXPANTHENOL

D-Pantothenyl Alcohol

d-Pantothenol

Ilopan

Motilyn

Pantenyl

Definitions

An alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47481

CAS_Registry

81-13-0

CHEBI_ID

CHEBI:27373

Chemical_Formula

C9H19NO4

code

C47481

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

An alcoholic analogue of D-pantothenic acid and cholinergic agent. Dexpanthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of dexpanthenol is unclear, it may enhance the effect of acetylcholine. Dexpanthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

FDA_UNII_Code

1O6C93RI7Z

FULL_SYN

D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide

Dexpanthenol

Provitamin B5

DEXPANTHENOL

D-Pantothenyl Alcohol

d-Pantothenol

Ilopan

Motilyn

Pantenyl

label

Dexpanthenol

Legacy Concept Name

Dexpanthenol

NCI_Drug_Dictionary_ID

675455

NSC Number

302962

PDQ_Closed_Trial_Search_ID

675455

PDQ_Open_Trial_Search_ID

675455

Preferred_Name

Dexpanthenol

prefixIRI

Thesaurus:C47481

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0057610

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26017

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