National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Propylene Oxide

Synonyms

1,2-Propylene Oxide

1,2-Epoxypropane

Propylene Oxide

PROPYLENE OXIDE

Methylethylene Oxide

Propene Oxide

Methyl Oxirane

Definitions

A synthetic, highly-flammable, volatile, colorless liquid that is soluble in water and miscible with many organic solvents. Propylene oxide is used primarily as a chemical intermediate in the production of polyethers and propylene glycol. It is also used as a pesticide and a fumigant for the sterilization of packaged foods and plastic medical instruments. Acute inhalation exposure to vapors of this compound can result in respiratory tract irritation, coughing, difficulty in breathing (dyspnea) and buildup of fluid in the lungs (pulmonary edema) that can possibly lead to pneumonia. Inhale high concentrations of the vapors for short time periods may cause headache, motor weakness, incoordination, ataxia and coma. Contact with propylene oxide can irritate the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C44438

CAS_Registry

75-56-9

CHEBI_ID

CHEBI:38685

Chemical_Formula

C3H6O

code

C44438

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic, highly-flammable, volatile, colorless liquid that is soluble in water and miscible with many organic solvents. Propylene oxide is used primarily as a chemical intermediate in the production of polyethers and propylene glycol. It is also used as a pesticide and a fumigant for the sterilization of packaged foods and plastic medical instruments. Acute inhalation exposure to vapors of this compound can result in respiratory tract irritation, coughing, difficulty in breathing (dyspnea) and buildup of fluid in the lungs (pulmonary edema) that can possibly lead to pneumonia. Inhale high concentrations of the vapors for short time periods may cause headache, motor weakness, incoordination, ataxia and coma. Contact with propylene oxide can irritate the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05)

FDA_UNII_Code

Y4Y7NYD4BK

FULL_SYN

1,2-Propylene Oxide

1,2-Epoxypropane

Propylene Oxide

PROPYLENE OXIDE

Methylethylene Oxide

Propene Oxide

Methyl Oxirane

label

Propylene Oxide

Legacy Concept Name

Propylene_Oxide

Preferred_Name

Propylene Oxide

prefixIRI

Thesaurus:C44438

Semantic_Type

Hazardous or Poisonous Substance

UMLS_CUI

C0072229

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45408

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