National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Propiolactone

Synonyms

Propiolactone

Beta-Propiolactone

2-Oxetanone

3-Propiolactone

3-Hydroxypropionic Acid, b-Lactone

Hydracrylic Acid, b-Lactone

3-Propanolide

b-Propionolactone

PROPIOLACTONE

Definitions

A colorless, highly reactive, liquid, cyclic ether with a slightly sweet odor. Beta-propiolactone was used once mainly in the manufacture of acrylic acid and esters. It also was used as a sterilant for medical materials and procedures. However, it is no longer used for medical disinfection. Dermal exposure to beta-propiolactone causes the burning or blistering of the skin, and ingestion of this substance burns the mouth and stomach while exposure to its vapors causes severe irritation of the eyes, throat and respiratory tract. This substance is reasonably anticipated to be a human carcinogen. (NCI05)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C44339

CAS_Registry

57-57-8

CHEBI_ID

CHEBI:49073

Chemical_Formula

C3H4O2

code

C44339

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A colorless, highly reactive, liquid, cyclic ether with a slightly sweet odor. Beta-propiolactone was used once mainly in the manufacture of acrylic acid and esters. It also was used as a sterilant for medical materials and procedures. However, it is no longer used for medical disinfection. Dermal exposure to beta-propiolactone causes the burning or blistering of the skin, and ingestion of this substance burns the mouth and stomach while exposure to its vapors causes severe irritation of the eyes, throat and respiratory tract. This substance is reasonably anticipated to be a human carcinogen. (NCI05)

FDA_UNII_Code

6RC3ZT4HB0

FULL_SYN

Propiolactone

Beta-Propiolactone

2-Oxetanone

3-Propiolactone

3-Hydroxypropionic Acid, b-Lactone

Hydracrylic Acid, b-Lactone

3-Propanolide

b-Propionolactone

PROPIOLACTONE

label

Propiolactone

Legacy Concept Name

Beta-Propiolactone

NSC Number

21626

Preferred_Name

Propiolactone

prefixIRI

Thesaurus:C44339

Semantic_Type

Pharmacologic Substance

Hazardous or Poisonous Substance

UMLS_CUI

C0033472

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C606

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45187

Delete Subject Author Type Created
No notes to display