National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Alkylation Process
Synonyms

Alkylation Process

Alkylation
Definitions

Alkylating Activity in biological systems is typically a process of covalent bonding in which a chemical substance replaces hydrogen atom(s) in biologically active molecules with alkyl radical(s), hindering proper function. DNA alkylation results in strand cross-linking and can inhibit DNA replication.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C40468
code

C40468
DEFINITION

Alkylating Activity in biological systems is typically a process of covalent bonding in which a chemical substance replaces hydrogen atom(s) in biologically active molecules with alkyl radical(s), hindering proper function. DNA alkylation results in strand cross-linking and can inhibit DNA replication.
FULL_SYN

Alkylation Process

Alkylation
label

Alkylation Process
Legacy Concept Name

Alkylating_Activity
Preferred_Name

Alkylation Process
prefixIRI

Thesaurus:C40468
Semantic_Type

Phenomenon or Process
UMLS_CUI

C0002074
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C19899
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