loading...| Preferred Name |
Colistin Sulfate |
|
| Synonyms |
Polymixin E Sulfate Coly-Mycin S Colistin Sulfate COLISTIN SULFATE N-(4-amino-1-(1-(4-amino-1-oxo-1-(3,12,23-tris(2-aminoethyl)- 20-(1-hydroxyethyl)-6,9-diisobutyl-2,5,8,11,14,19,22-heptaoxo- 1,4,7,10,13,18-hexaazacyclotricosan-15-ylamino)butan-2-ylamino)- 3-hydroxybutan-2-ylamino)-1-oxobutan-2-yl)-N,5-dimethylheptanamide;sulfuric acid |
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| Definitions |
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. (Medical Dictionary Online) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C386 |
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| CAS_Registry |
1264-72-8 |
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| code |
C386 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally. (Medical Dictionary Online) |
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| FDA_UNII_Code |
WP15DXU577 |
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| FULL_SYN |
Polymixin E Sulfate Coly-Mycin S Colistin Sulfate COLISTIN SULFATE N-(4-amino-1-(1-(4-amino-1-oxo-1-(3,12,23-tris(2-aminoethyl)- 20-(1-hydroxyethyl)-6,9-diisobutyl-2,5,8,11,14,19,22-heptaoxo- 1,4,7,10,13,18-hexaazacyclotricosan-15-ylamino)butan-2-ylamino)- 3-hydroxybutan-2-ylamino)-1-oxobutan-2-yl)-N,5-dimethylheptanamide;sulfuric acid |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Colistin Sulfate |
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| Legacy Concept Name |
Colistin_Sulfate |
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| NCI_Drug_Dictionary_ID |
41545 |
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| PDQ_Closed_Trial_Search_ID |
41545 |
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| PDQ_Open_Trial_Search_ID |
41545 |
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| Preferred_Name |
Colistin Sulfate |
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| prefixIRI |
Thesaurus:C386 |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance Antibiotic |
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| UMLS_CUI |
C0009317 |
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| subClassOf |