National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Hypoxanthine-Guanine Phosphoribosyltransferase

Synonyms

Hypoxanthine Phosphoribosyltransferase 1

Hypoxanthine-Guanine Phosphoribosyltransferase

EC 2.4.2.8

HGPRT

HGPRTase

HPRT1

Definitions

Hypoxanthine-guanine phosphoribosyltransferase (218 aa, ~25 kDa) is encoded by the human HPRT1 gene. This protein plays a role in nucleoside metabolism.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38496

code

C38496

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Hypoxanthine-guanine phosphoribosyltransferase (218 aa, ~25 kDa) is encoded by the human HPRT1 gene. This protein plays a role in nucleoside metabolism.

DesignNote

Protein_Plays_Role_In_Biological_Process: Purine Salvage

Display_Name

Hypoxanthine-Guanine Phosphoribosyltransferase

FULL_SYN

Hypoxanthine Phosphoribosyltransferase 1

Hypoxanthine-Guanine Phosphoribosyltransferase

EC 2.4.2.8

HGPRT

HGPRTase

HPRT1

label

Hypoxanthine-Guanine Phosphoribosyltransferase

Legacy Concept Name

Hypoxanthine_Phosphoribosyltransferase-1

NCI_META_CUI

CL322751

OMIM_Number

308000

Preferred_Name

Hypoxanthine-Guanine Phosphoribosyltransferase

prefixIRI

Thesaurus:C38496

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Swiss_Prot

P00492

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17434

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