loading...| Preferred Name | Clomiphene Citrate | |
| Synonyms |
CLOMIPHENE CITRATE 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine Citrate Clomiphene Citrate 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine Citrate (1:1) Clomid Serophene |
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| Definitions |
The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C379 |
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| CAS_Registry |
50-41-9 |
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| CHEBI_ID |
CHEBI:3753 |
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| code |
C379 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
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| Contributing_Source |
FDA GDC |
|
| DEFINITION |
The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04) |
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| FDA_UNII_Code |
1B8447E7YI |
|
| FULL_SYN |
CLOMIPHENE CITRATE 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine Citrate Clomiphene Citrate 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine Citrate (1:1) Clomid Serophene |
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| Has_Free_Acid_Or_Base_Form | ||
| Is_Value_For_GDC_Property | ||
| label |
Clomiphene Citrate |
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| Legacy Concept Name |
Clomiphene |
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| Maps_To |
Clomiphene Citrate |
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| NCI_Drug_Dictionary_ID |
39542 |
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| NSC Number |
35770 |
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| PDQ_Closed_Trial_Search_ID |
39542 |
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| PDQ_Open_Trial_Search_ID |
39542 |
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| Preferred_Name |
Clomiphene Citrate |
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| prefixIRI |
Thesaurus:C379 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0546859 |
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| subClassOf |