National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Jump to:
loading...
Preferred Name

Interferon Alpha/Beta Receptor 2
Synonyms

Interferon Alpha-Beta Receptor

IFN-Alpha-REC

Interferon-Alpha/Beta Receptor Beta Chain

Interferon Alpha/Beta Receptor 2

Interferon Alpha-Beta Receptor Beta Chain

Type I Interferon Receptor

Type I Interferon Receptor 2

Alpha-Beta-Omega Interferon Receptor-2

Interferon Alpha Binding Protein

Interferon Alpha-Beta Receptor-2

IFN-Alpha Binding Protein

IFN-Alpha/Beta Receptor 2

IFN-R

IFNABR
Definitions

Interferon alpha/beta receptor 2 (515 aa, ~58 kDa) is encoded by the human IFNAR2 gene. This protein is involved in interferon signaling.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C37278
code

C37278
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177415
Contributing_Source

CTRP
DEFINITION

Interferon alpha/beta receptor 2 (515 aa, ~58 kDa) is encoded by the human IFNAR2 gene. This protein is involved in interferon signaling.
DesignNote

Interferon alpha/beta receptor 2 is the beta subunit of the interferon alpha receptor complex, a heterodimeric receptor for type I IFNs, alpha and beta, which also includes interferon alpha/beta receptor 1. Binding of alpha and beta IFNs mediate innate immune responses to viral infection and specific interferon inhibition of virus replication, triggers tyrosine phosphorylation of JAK and STAT proteins, and autophosphorylation of and tyrosine phosphorylation by TYK2. IFNAR2 also interacts with RACK1.
Display_Name

Interferon Alpha/Beta Receptor 2
FULL_SYN

Interferon Alpha-Beta Receptor

IFN-Alpha-REC

Interferon-Alpha/Beta Receptor Beta Chain

Interferon Alpha/Beta Receptor 2

Interferon Alpha-Beta Receptor Beta Chain

Type I Interferon Receptor

Type I Interferon Receptor 2

Alpha-Beta-Omega Interferon Receptor-2

Interferon Alpha Binding Protein

Interferon Alpha-Beta Receptor-2

IFN-Alpha Binding Protein

IFN-Alpha/Beta Receptor 2

IFN-R

IFNABR
label

Interferon Alpha/Beta Receptor 2
Legacy Concept Name

Interferon_Alpha-Beta_Receptor_Beta_Chain
OMIM_Number

602376
Preferred_Name

Interferon Alpha/Beta Receptor 2
prefixIRI

Thesaurus:C37278
Semantic_Type

Amino Acid, Peptide, or Protein

Receptor
Swiss_Prot

P48551
UMLS_CUI

C1568206
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17667
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display