National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Digestive System Adenoma

Synonyms

Gastrointestinal System Adenoma

Digestive System Adenoma

GI System Adenoma

Definitions

A sporadic or less frequently familial neoplasm that arises from the glandular epithelium of the gastrointestinal tract and liver. In the gastrointestinal tract, it manifests as a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and is associated with dysplasia. Based on the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger gastrointestinal tract adenomas with severe dysplastic changes carry a higher risk of progression to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. In the liver, it arises from the hepatocytes. Grossly, it appears as a soft, round mass. Morphologically, the neoplastic cells resemble normal hepatocytes.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36207

code

C36207

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C126659

DEFINITION

A sporadic or less frequently familial neoplasm that arises from the glandular epithelium of the gastrointestinal tract and liver. In the gastrointestinal tract, it manifests as a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and is associated with dysplasia. Based on the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger gastrointestinal tract adenomas with severe dysplastic changes carry a higher risk of progression to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. In the liver, it arises from the hepatocytes. Grossly, it appears as a soft, round mass. Morphologically, the neoplastic cells resemble normal hepatocytes.

FULL_SYN

Gastrointestinal System Adenoma

Digestive System Adenoma

GI System Adenoma

label

Digestive System Adenoma

Legacy Concept Name

Gastrointestinal_Adenoma

Neoplastic_Status

Benign

Preferred_Name

Digestive System Adenoma

prefixIRI

Thesaurus:C36207

Semantic_Type

Neoplastic Process

UMLS_CUI

C0948101

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C4787

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2855

Delete Subject Author Type Created
No notes to display