National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3423
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3423
Preferred Name

Tuberculosis
Definitions
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use.
Synonyms
Tuberculosis Disease
Active Tuberculosis
Tuberculosis
tuberculosis
TB
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
Tuberculosis
Maps_To
Tuberculosis
Legacy Concept Name
Tuberculosis
Is_Value_For_GDC_Property
Preferred_Name
Tuberculosis
Semantic_Type
Disease or Syndrome
prefixIRI
Thesaurus:C3423
DEFINITION
A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use.
UMLS_CUI
C0041296
code
C3423
subClassOf
type
FULL_SYN
Tuberculosis Disease
Active Tuberculosis
Tuberculosis
tuberculosis
TB
ALT_DEFINITION
A disease caused by Mycobacterium tuberculosis infection that is characterized by the growth of nodules in body tissues, most commonly the lungs, and may be transmitted through droplets from the throat or lungs of individuals with the active respiratory disease.
Contributing_Source
CPTAC
GDC
MedDRA
NICHD
Concept_In_Subset
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