National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Butyrophenone

Synonyms

1-phenylbutan-1-one

Butyrophenone

BUTYROPHENONE

Definitions

Synthetic agents containing the phenyl-1-butanone group, most Butyrophenones are neuroleptic (antipsychotic) drugs, such as haloperidol, droperidol, or azaperone, that control schizophrenic symptoms (hallucinations, delusions, dementia). Most antipsychotic agents interfere with neurotransmitter functions, usually blocking dopamine receptors, and induce behavioral, endocrine, motor-kinetic effects. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C323

CAS_Registry

495-40-9

Chemical_Formula

C10H12O

code

C323

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

Synthetic agents containing the phenyl-1-butanone group, most Butyrophenones are neuroleptic (antipsychotic) drugs, such as haloperidol, droperidol, or azaperone, that control schizophrenic symptoms (hallucinations, delusions, dementia). Most antipsychotic agents interfere with neurotransmitter functions, usually blocking dopamine receptors, and induce behavioral, endocrine, motor-kinetic effects. (NCI04)

FDA_UNII_Code

186I11WB5B

FULL_SYN

1-phenylbutan-1-one

Butyrophenone

BUTYROPHENONE

label

Butyrophenone

Legacy Concept Name

Butyrophenone

Preferred_Name

Butyrophenone

prefixIRI

Thesaurus:C323

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0006525

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C78272

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