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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3099
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3099
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|---|---|
| Preferred Name | Hepatocellular Carcinoma |
| Definitions |
A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.
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| Synonyms |
Hepatocellular carcinoma
Hepatocellular Cancer
Carcinoma of Liver Cells
hepatocellular carcinoma
Liver Cell Carcinoma
Primary Carcinoma of the Liver Cells
CARCINOMA, HEPATOCELLULAR, MALIGNANT
Carcinoma of the Liver Cells
Primary Carcinoma of Liver Cells
Liver Cell Cancer (Hepatocellular Carcinoma)
Liver cell carcinoma
Hepatocellular Carcinoma
HCC
Hepatoma
LIHC
hepatoma
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Hepatocellular Carcinoma
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|---|---|
| Maps_To |
Hepatoma, malignant
Malignant neoplasm: Liver cell carcinoma
Hepatocarcinoma
Liver cell carcinoma
Hepatocellular carcinoma, NOS
Hepatoma, NOS
8170/3
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| Neoplastic_Status |
Malignant
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| Legacy Concept Name |
Hepatocellular_Carcinoma
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| Neoplasm_Has_Special_Category | |
| Is_Value_For_GDC_Property | |
| ICD-O-3_Code |
8170/3
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| Preferred_Name |
Hepatocellular Carcinoma
|
| Display_Name |
Hepatocellular Carcinoma
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| Semantic_Type |
Neoplastic Process
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| prefixIRI |
Thesaurus:C3099
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| DEFINITION |
A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation.
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| UMLS_CUI |
C0019204
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| code |
C3099
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| subClassOf | |
| type | |
| FULL_SYN |
Hepatocellular carcinoma
Hepatocellular Cancer
Carcinoma of Liver Cells
hepatocellular carcinoma
Liver Cell Carcinoma
Primary Carcinoma of the Liver Cells
CARCINOMA, HEPATOCELLULAR, MALIGNANT
Carcinoma of the Liver Cells
Primary Carcinoma of Liver Cells
Liver Cell Cancer (Hepatocellular Carcinoma)
Liver cell carcinoma
Hepatocellular Carcinoma
HCC
Hepatoma
LIHC
hepatoma
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|
| ALT_DEFINITION |
A malignant neoplasm arising from hepatocytes.
A type of adenocarcinoma and the most common type of liver tumor.
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| Contributing_Source |
Cellosaurus
CDISC
CPTAC
CTEP
CTRP
GDC
mCode
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| Concept_In_Subset |
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