National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Lidocaine Topical
Synonyms

Lidocaine Topical
Definitions

A synthetic aminoethylamide with local anesthetic activity applied topically to either the skin or mucous membranes. Lidocaine stabilizes the neuronal cell membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the initiation and conduction of nerve impulses and producing a reversible loss of sensation.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29989
code

C29989
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977
Contributing_Source

CTRP
DEFINITION

A synthetic aminoethylamide with local anesthetic activity applied topically to either the skin or mucous membranes. Lidocaine stabilizes the neuronal cell membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the initiation and conduction of nerve impulses and producing a reversible loss of sensation.
Display_Name

Lidocaine Topical
FULL_SYN

Lidocaine Topical
label

Lidocaine Topical
Legacy Concept Name

Lidocaine_Topical
NCI_Drug_Dictionary_ID

793948
PDQ_Closed_Trial_Search_ID

793948
PDQ_Open_Trial_Search_ID

793948
Preferred_Name

Lidocaine Topical
prefixIRI

Thesaurus:C29989
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0360097
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C245
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