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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29613
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29613
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Preferred Name | Serine |
Definitions |
A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)
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Synonyms |
(S)-2-Amino-3-hydroxy-propanoic acid
beta-Hydroxyalanine
2-Amino-3-hydroxypropionic Acid
SERINE
Ser
Serine
l-Serine
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
label |
Serine
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Legacy Concept Name |
Serine
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CHEBI_ID |
CHEBI:17115
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Preferred_Name |
Serine
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Display_Name |
Serine
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Semantic_Type |
Amino Acid, Peptide, or Protein
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prefixIRI |
Thesaurus:C29613
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DEFINITION |
A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)
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UMLS_CUI |
C0036720
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code |
C29613
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Chemical_Formula |
C3H7NO3
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Unit |
g
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USDA_ID |
518
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INFOODS |
SER_G
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subClassOf | |
NSC Number |
118365
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type | |
CAS_Registry |
56-45-1
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FULL_SYN |
(S)-2-Amino-3-hydroxy-propanoic acid
beta-Hydroxyalanine
2-Amino-3-hydroxypropionic Acid
SERINE
Ser
Serine
l-Serine
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FDA_UNII_Code |
452VLY9402
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ALT_DEFINITION |
Amino acid with side chain -CH2OH.
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Contributing_Source |
CRCH
CTRP
FDA
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Concept_In_Subset |
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