loading...| Preferred Name | Rifamycin | |
| Synonyms |
5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-B)furan-1,11(2h)-dione 21-Acetate Rifamycin SV M-14 RIFAMYCIN Rifamycin |
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| Definitions |
A natural antibiotic produced by Streptomyces mediterranei, Rifamycin (Ansamycin Family) is a commonly used antimycobacterial drug that inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis; it blocks RNA-polymerase transcription initiation. Rifamycin has an activity spectrum against Gram-positive and Gram-negative bacteria, but is mainly used against Mycobacterium sp. (especially M. tuberculosis) in association with other agents to overcome resistance. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29406 |
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| Accepted_Therapeutic_Use_For |
Treatment of traveler's diarrhea |
|
| CAS_Registry |
6998-60-3 |
|
| CHEBI_ID |
CHEBI:26580 |
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| Chemical_Formula |
C37H47NO12 |
|
| code |
C29406 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A natural antibiotic produced by Streptomyces mediterranei, Rifamycin (Ansamycin Family) is a commonly used antimycobacterial drug that inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis; it blocks RNA-polymerase transcription initiation. Rifamycin has an activity spectrum against Gram-positive and Gram-negative bacteria, but is mainly used against Mycobacterium sp. (especially M. tuberculosis) in association with other agents to overcome resistance. (NCI04) |
|
| FDA_UNII_Code |
DU69T8ZZPA |
|
| FULL_SYN |
5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-B)furan-1,11(2h)-dione 21-Acetate Rifamycin SV M-14 RIFAMYCIN Rifamycin |
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| Has_Salt_Form | ||
| label |
Rifamycin |
|
| Legacy Concept Name |
Rifamycin |
|
| NCI_META_CUI |
CL560681 |
|
| NSC Number |
145604 |
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| Preferred_Name |
Rifamycin |
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| prefixIRI |
Thesaurus:C29406 |
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| Semantic_Type |
Pharmacologic Substance |
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| subClassOf |