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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Pramipexole Dihydrochloride | |
| Synonyms |
Pramipexole Dihydrochloride PRAMIPEXOLE DIHYDROCHLORIDE Mirapex |
|
| Definitions |
The hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and substantia nigra of the brain. Compared to other dopamine agonists, the use of this agent may be associated with fewer dyskinetic side effects in treated subjects. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29374 |
|
| CAS_Registry |
191217-81-9
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|
| CHEBI_ID |
CHEBI:51147
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|
| Chemical_Formula |
C10H17N3S.2HCl.H2O
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|
| code |
C29374
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|
| Concept_In_Subset | ||
| Contributing_Source |
FDA
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| DEFINITION |
The hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and substantia nigra of the brain. Compared to other dopamine agonists, the use of this agent may be associated with fewer dyskinetic side effects in treated subjects. (NCI04)
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|
| FDA_UNII_Code |
3D867NP06J
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|
| FULL_SYN |
Pramipexole Dihydrochloride PRAMIPEXOLE DIHYDROCHLORIDE Mirapex
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Pramipexole Dihydrochloride
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|
| Legacy Concept Name |
Pramipexole_Dihydrochloride
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|
| NCI_Drug_Dictionary_ID |
779012
|
|
| PDQ_Closed_Trial_Search_ID |
779012
|
|
| PDQ_Open_Trial_Search_ID |
779012
|
|
| Preferred_Name |
Pramipexole Dihydrochloride
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|
| prefixIRI |
Thesaurus:C29374
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0772054
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|
| subClassOf |
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