National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Pancrelipase
Synonyms

Pancrelipase

PANCRELIPASE

Creon

Pancrease

Ultresa

Viokace

Zenpep

Zymase

Definitions

A standardized enzyme concentrate containing the pancreatic enzymes, lipase, protease and amylase used in enzyme substitution therapy. Lipase, protease and amylase break down fat, protein, and starches, respectively in the small intestine, thereby promoting digestion. Pancrelipase is used to reduce malabsorption when the pancreas is unable to secrete sufficient amounts of these enzymes.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29345

Accepted_Therapeutic_Use_For

exocrine pancreatic insufficiency; pancreatic enzyme deficiency

CAS_Registry

53608-75-6

code

C29345

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

A standardized enzyme concentrate containing the pancreatic enzymes, lipase, protease and amylase used in enzyme substitution therapy. Lipase, protease and amylase break down fat, protein, and starches, respectively in the small intestine, thereby promoting digestion. Pancrelipase is used to reduce malabsorption when the pancreas is unable to secrete sufficient amounts of these enzymes.

Display_Name

Pancrelipase

FDA_UNII_Code

FQ3DRG0N5K

FULL_SYN

Pancrelipase

PANCRELIPASE

Creon

Pancrease

Ultresa

Viokace

Zenpep

Zymase

label

Pancrelipase

Legacy Concept Name

Pancrelipase

NCI_Drug_Dictionary_ID

43514

PDQ_Closed_Trial_Search_ID

43514

PDQ_Open_Trial_Search_ID

43514

Preferred_Name

Pancrelipase

prefixIRI

Thesaurus:C29345

Semantic_Type

Amino Acid, Peptide, or Protein

Pharmacologic Substance

UMLS_CUI

C0770343

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29726

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