National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Omalizumab
Synonyms

Anti-IgE Monoclonal Antibody E25

IGE 025

OMALIZUMAB

Olizumab

Omalizumab

Xolair

rhuMAb-E25

Definitions

A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29299

CAS_Registry

242138-07-4

code

C29299

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. (NCI04)

FDA_UNII_Code

2P471X1Z11

FULL_SYN

Anti-IgE Monoclonal Antibody E25

IGE 025

OMALIZUMAB

Olizumab

Omalizumab

Xolair

rhuMAb-E25

label

Omalizumab

Legacy Concept Name

Olizumab

Preferred_Name

Omalizumab

prefixIRI

Thesaurus:C29299

Semantic_Type

Amino Acid, Peptide, or Protein

Pharmacologic Substance

Immunologic Factor

UMLS_CUI

C0966225

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20401

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