National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Isoproterenol Hydrochloride
Synonyms

4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol Hydrochloride

ISOPROTERENOL HYDROCHLORIDE

Isoproterenol Hydrochloride

Isuprel

Definitions

The hydrochloride salt form of isoproterenol, a synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating properties. Isoproterenol exerts its effect on the beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and cardiac output. In addition, isoproterenol acts on beta-2 adrenergic receptors in bronchiolar and vascular smooth muscle, thereby causing smooth muscle relaxation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29133

CAS_Registry

51-30-9

Chemical_Formula

C11H17NO3.HCl

code

C29133

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of isoproterenol, a synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating properties. Isoproterenol exerts its effect on the beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and cardiac output. In addition, isoproterenol acts on beta-2 adrenergic receptors in bronchiolar and vascular smooth muscle, thereby causing smooth muscle relaxation.

FDA_UNII_Code

DIA2A74855

FULL_SYN

4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol Hydrochloride

ISOPROTERENOL HYDROCHLORIDE

Isoproterenol Hydrochloride

Isuprel

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62041

label

Isoproterenol Hydrochloride

Legacy Concept Name

Isoproterenol

NSC Number

37745

89747

Preferred_Name

Isoproterenol Hydrochloride

prefixIRI

Thesaurus:C29133

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0282210

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C319

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