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National Cancer Institute Thesaurus
| Preferred Name | Famotidine | |
| Synonyms |
FAMOTIDINE Famotidine Pepcid Pepcid AC |
|
| Definitions |
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29045 |
|
| CAS_Registry |
76824-35-6
|
|
| CHEBI_ID |
CHEBI:4975
|
|
| Chemical_Formula |
C8H15N7O2S3
|
|
| code |
C29045
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 |
|
| Contributing_Source |
CTRP FDA HemOnc
|
|
| DEFINITION |
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.
|
|
| Display_Name |
Famotidine
|
|
| FDA_UNII_Code |
5QZO15J2Z8
|
|
| FULL_SYN |
FAMOTIDINE Famotidine Pepcid Pepcid AC
|
|
| Has_Target | ||
| label |
Famotidine
|
|
| Legacy Concept Name |
Famotidine
|
|
| NCI_Drug_Dictionary_ID |
574268
|
|
| PDQ_Closed_Trial_Search_ID |
574268
|
|
| PDQ_Open_Trial_Search_ID |
574268
|
|
| Preferred_Name |
Famotidine
|
|
| prefixIRI |
Thesaurus:C29045
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0015620
|
|
| subClassOf |
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