National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Jump to:
Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29033
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29033
Preferred Name

Ethambutol Hydrochloride
Definitions
The hydrochloride salt form of ethambutol, an ethylenediamine derivative with antibacterial activity, specifically effective against mycobacteria. Although the exact mechanism of action of ethambutol hydrochloride is unknown, ethambutol hydrochloride inhibits the transfer of mycolic acids into the cell wall of bacteria, which impedes bacterial cell growth. This agent may also interfere with RNA synthesis or inhibit other cell metabolism, thereby preventing cell multiplication and causing cell death.
Synonyms
Ethambutol HCl
ETHAMBUTOL HYDROCHLORIDE
Ethambutol Hydrochloride
Myambutol
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
Ethambutol Hydrochloride
Legacy Concept Name
Ethambutol_Hydrochloride
CHEBI_ID
CHEBI:4878
Preferred_Name
Ethambutol Hydrochloride
Semantic_Type
Organic Chemical
Pharmacologic Substance
prefixIRI
Thesaurus:C29033
DEFINITION
The hydrochloride salt form of ethambutol, an ethylenediamine derivative with antibacterial activity, specifically effective against mycobacteria. Although the exact mechanism of action of ethambutol hydrochloride is unknown, ethambutol hydrochloride inhibits the transfer of mycolic acids into the cell wall of bacteria, which impedes bacterial cell growth. This agent may also interfere with RNA synthesis or inhibit other cell metabolism, thereby preventing cell multiplication and causing cell death.
UMLS_CUI
C0546863
code
C29033
Chemical_Formula
C10H24N2O2.2HCl
subClassOf
type
CAS_Registry
1070-11-7
FULL_SYN
Ethambutol HCl
ETHAMBUTOL HYDROCHLORIDE
Ethambutol Hydrochloride
Myambutol
FDA_UNII_Code
QE4VW5FO07
Contributing_Source
FDA
Concept_In_Subset
Has_Free_Acid_Or_Base_Form
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display