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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Cholestyramine | |
| Synonyms |
Colestyramine Cholestyramine Duolite AP143 Resin Questran Light CHOLESTYRAMINE Cholybar Questran |
|
| Definitions |
An anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble complex, which is then excreted in the feces, resulting in an increased oxidation of cholesterol to bile acids, a decrease in low density lipoprotein in the plasma, and a decrease in serum cholesterol levels. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28929 |
|
| CAS_Registry |
11041-12-6
|
|
| Chemical_Formula |
(C12H18ClN)n.(C10H10)n
|
|
| code |
C28929
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
An anion exchange resin with hypolipidemic activity. Cholestyramine resin adsorbs and combines with bile acids in the intestine to form an insoluble complex, which is then excreted in the feces, resulting in an increased oxidation of cholesterol to bile acids, a decrease in low density lipoprotein in the plasma, and a decrease in serum cholesterol levels.
|
|
| Display_Name |
Cholestyramine
|
|
| FDA_UNII_Code |
4B33BGI082
|
|
| FULL_SYN |
Colestyramine Cholestyramine Duolite AP143 Resin Questran Light CHOLESTYRAMINE Cholybar Questran
|
|
| label |
Cholestyramine
|
|
| Legacy Concept Name |
Cholestyramine
|
|
| NCI_Drug_Dictionary_ID |
813330
|
|
| NSC Number |
177361
|
|
| Preferred_Name |
Cholestyramine
|
|
| prefixIRI |
Thesaurus:C28929
|
|
| Semantic_Type |
Pharmacologic Substance
|
|
| UMLS_CUI |
C0008402
|
|
| subClassOf |
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