National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Id http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28912
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28912
Preferred Name

Cefadroxil

Definitions
A semi-synthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cefadroxil binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Synonyms
(6R,7R)-7-(((2R)-Amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
CEFADROXIL
Cefadroxil
Duricef
Type http://www.w3.org/2002/07/owl#Class
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Notes

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Delete Subject Subject Sort Archive Sort Author Type Class Created
New concept - total skin sparing mastectomy     New concept - total skin sparing mastectomy false anonymous Comment http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C15277 2013-05-22
causes and symptoms     causes and symptoms false linairis Comment 2009-08-06
Test note     Test note false decorons Comment 2011-02-07
    false decorons Comment 2008-12-31
An image example for melanoma     An image example for melanoma false jonquet Comment 2008-08-06
    false decorons Comment 2008-12-31
    false decorons Comment 2008-12-31
Wikipedia page on 'melanoma'     Wikipedia page on 'melanoma' false jonquet Comment 2008-08-06
Antineoplastic antibiotics are antibiotics (?)     Antineoplastic antibiotics are antibiotics (?) false coulet Comment 2013-01-25
New Term Proposal: abcd     New Term Proposal: abcd false fergerson New Class Proposal 2010-12-17
NIH-What Causes COPD     NIH-What Causes COPD false linairis Comment 2009-08-06
The treatment of COPD     The treatment of COPD false linairis Comment 2009-08-06
relationship with Smoking Behavior     relationship with Smoking Behavior false pkcourtney Comment 2010-06-22
RE: Antineoplastic antibiotics are antibiotics (?)     RE: Antineoplastic antibiotics are antibiotics (?) false rwynne Comment 2013-02-13
    false decorons Comment 2008-12-31
MedlinePlus     MedlinePlus false linairis Comment 2009-08-06
/ontologies/NCIT/notes/https%3A%2F%2Fdata.bioontology.org%2Fnotes%2F8dfd5db0-bd90-0136-3c5b-005056010073     false tabasco_tabata%40yahoo.co.jp Comment 2018-10-29
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