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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Id | http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28838
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28838
|
|---|---|
| Preferred Name | Atovaquone |
| Definitions |
A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.
|
| Synonyms |
566C80
ATOVAQUONE
Atovaquone
BW-566C
BW-A566C
Mepron
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Atovaquone
|
|---|---|
| Legacy Concept Name |
Atovoquone
|
| CHEBI_ID |
CHEBI:575568
|
| NCI_Drug_Dictionary_ID |
797848
|
| PDQ_Closed_Trial_Search_ID |
797848
|
| Preferred_Name |
Atovaquone
|
| Semantic_Type |
Pharmacologic Substance
|
| prefixIRI |
Thesaurus:C28838
|
| DEFINITION |
A synthetic hydroxynaphthoquinone with antiprotozoal activity. Atovoquone blocks the mitochondrial electron transport at complex III of the respiratory chain of protozoa, thereby inhibiting pyrimidine synthesis, preventing DNA synthesis and leading to protozoal death.
|
| UMLS_CUI |
C0165603
|
| code |
C28838
|
| Chemical_Formula |
C22H19ClO3
|
| subClassOf | |
| type | |
| CAS_Registry |
95233-18-4
|
| FULL_SYN |
566C80
ATOVAQUONE
Atovaquone
BW-566C
BW-A566C
Mepron
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|
| FDA_UNII_Code |
Y883P1Z2LT
|
| PDQ_Open_Trial_Search_ID |
797848
|
| Contributing_Source |
FDA
HemOnc
|
| Concept_In_Subset |
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