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National Cancer Institute Thesaurus
Preferred Name | Aspirin | |
Synonyms |
2-(Acetyloxy)benzoic Acid Acetylsalicylic acid Acetylsalicylic Acid ASA ASPIRIN Aspergum Aspirin Ecotrin Empirin Entericin Extren Measurin aspirin |
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Definitions |
An orally administered non-steroidal antiinflammatory agent. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C287 |
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Accepted_Therapeutic_Use_For |
Mild to moderate pain; fever; prevention of arterial and venous thrombosis
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ALT_DEFINITION |
Acetylsalicylic acid decreases synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties. A drug that reduces pain, fever, inflammation, and blood clotting. Aspirin belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is also being studied in cancer prevention.
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CAS_Registry |
50-78-2
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CHEBI_ID |
CHEBI:15365
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Chemical_Formula |
C9H8O4
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code |
C287
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Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191670 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191405 |
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Contributing_Source |
ACC/AHA CTRP FDA GDC HemOnc
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DEFINITION |
An orally administered non-steroidal antiinflammatory agent. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties.
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Display_Name |
Aspirin
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FDA_UNII_Code |
R16CO5Y76E
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FULL_SYN |
2-(Acetyloxy)benzoic Acid Acetylsalicylic acid Acetylsalicylic Acid ASA ASPIRIN Aspergum Aspirin Ecotrin Empirin Entericin Extren Measurin aspirin
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Has_ACC-AHA_SARS2_Authorized_Value |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17998 |
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Has_Salt_Form |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C83539 |
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Has_Target | ||
Is_Value_For_GDC_Property | ||
label |
Aspirin
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Legacy Concept Name |
Acetylsalicylic_Acid
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Maps_To |
Aspirin
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NCI_Drug_Dictionary_ID |
39152
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NSC Number |
406186
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PDQ_Closed_Trial_Search_ID |
39152
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PDQ_Open_Trial_Search_ID |
39152
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Preferred_Name |
Aspirin
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prefixIRI |
Thesaurus:C287
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Semantic_Type |
Organic Chemical Pharmacologic Substance
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UMLS_CUI |
C0004057
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subClassOf |
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