National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Mitochondrial DNA
Synonyms

M Chromosome

Mitochondrial Chromosome

Mitochondrial DNA

Chromosome M

chrM

mDNA

mtDNA

Definitions

Typically small, circular, intronless, and maternally inherited, mitochondrial DNA (mtDNA) is the multicopy deoxyribonucleic acid genome of mitochondria, intracellular organelles responsible for vital respiratory chain and oxidative phosphorylation reactions in higher eukaryotes. Replicated and transcribed by a separate enzymatic machinery from that of nuclear DNA, mtDNA encodes only a subset of mitochondrial functions. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28512

ALT_DEFINITION

Typically small, circular, intronless, and maternally inherited, mitochondrial DNA (mtDNA) is the multicopy deoxyribonucleic acid genome of mitochondria, intracellular organelles responsible for vital respiratory chain and oxidative phosphorylation reactions in higher eukaryotes. Replicated and transcribed by a separate enzymatic machinery from that of nuclear DNA, mtDNA encodes only a subset of mitochondrial functions.

code

C28512

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C111114

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C177537

Contributing_Source

CDISC

CTRP

GDC

DEFINITION

Typically small, circular, intronless, and maternally inherited, mitochondrial DNA (mtDNA) is the multicopy deoxyribonucleic acid genome of mitochondria, intracellular organelles responsible for vital respiratory chain and oxidative phosphorylation reactions in higher eukaryotes. Replicated and transcribed by a separate enzymatic machinery from that of nuclear DNA, mtDNA encodes only a subset of mitochondrial functions. (NCI04)

Display_Name

Mitochondrial DNA

FULL_SYN

M Chromosome

Mitochondrial Chromosome

Mitochondrial DNA

Chromosome M

chrM

mDNA

mtDNA

Is_Value_For_GDC_Property

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C13202

label

Mitochondrial DNA

Legacy Concept Name

Mitochondrial_DNA

Maps_To

chrM

Preferred_Name

Mitochondrial DNA

prefixIRI

Thesaurus:C28512

Semantic_Type

Nucleic Acid, Nucleoside, or Nucleotide

UMLS_CUI

C0012929

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C449

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