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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Coagulation Factor IX | |
| Synonyms |
EC 3.4.21.22 Christmas Factor Plasma Thromboplastin Component Coagulation Factor IX Plasma Thromboplastic Component F9 Factor 9 Factor IX PTC |
|
| Definitions |
Coagulation factor IX (461 aa, ~52 kDa) is encoded by the human F9 gene. This protein plays a role in the intrinsic pathway of blood coagulation through the mediation of proteolysis that converts factor X into an active protease. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28482 |
|
| code |
C28482
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP
|
|
| DEFINITION |
Coagulation factor IX (461 aa, ~52 kDa) is encoded by the human F9 gene. This protein plays a role in the intrinsic pathway of blood coagulation through the mediation of proteolysis that converts factor X into an active protease.
|
|
| DesignNote |
Coagulation factor IX is converted from a zymogen to an active protease through a single proteolytic cleavage by either coagulation factor XIa or a complex containing tissue factor and coagulation factor IIVa.
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|
| Display_Name |
Coagulation Factor IX
|
|
| FULL_SYN |
EC 3.4.21.22 Christmas Factor Plasma Thromboplastin Component Coagulation Factor IX Plasma Thromboplastic Component F9 Factor 9 Factor IX PTC
|
|
| label |
Coagulation Factor IX
|
|
| Legacy Concept Name |
Coagulation_Factor-IX
|
|
| OMIM_Number |
300746
|
|
| Preferred_Name |
Coagulation Factor IX
|
|
| prefixIRI |
Thesaurus:C28482
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|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme
|
|
| Swiss_Prot |
P00740
|
|
| UMLS_CUI |
C0015491
|
|
| subClassOf |
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