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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Endothelin Receptor Type A Antagonist | |
| Synonyms |
endothelin-1 protein receptor antagonist Endothelin-1 Protein Receptor Antagonist Endothelin Receptor Type A Antagonist ETA Receptor Antagonist |
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| Definitions |
A group of agents that bind to the endothelin-1 receptor (primarily endothelin-A receptor, or ET-A), thereby inhibiting tumor cell proliferation and tumor associated angiogenesis. (NCI04) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28334 |
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| ALT_DEFINITION |
A substance that blocks the binding of the endothelin-1 protein to its receptor. Endothelin-1 is a small molecule that causes changes in blood vessels and helps regulate blood pressure. It can also stimulate the growth of some types of cells.
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| code |
C28334
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| DEFINITION |
A group of agents that bind to the endothelin-1 receptor (primarily endothelin-A receptor, or ET-A), thereby inhibiting tumor cell proliferation and tumor associated angiogenesis. (NCI04)
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| FULL_SYN |
endothelin-1 protein receptor antagonist Endothelin-1 Protein Receptor Antagonist Endothelin Receptor Type A Antagonist ETA Receptor Antagonist
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| label |
Endothelin Receptor Type A Antagonist
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| Legacy Concept Name |
Endothelin-1_Protein_Receptor_Antagonist
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| Preferred_Name |
Endothelin Receptor Type A Antagonist
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| prefixIRI |
Thesaurus:C28334
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| Semantic_Type |
Chemical Viewed Functionally
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| UMLS_CUI |
C1516869
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| subClassOf |
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