National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Antioxidant
Synonyms

antioxidant

Antioxidant

Definitions

A group of organic or inorganic substances capable of preventing the genotoxic and carcinogenic effects of free-radical compounds. Antioxidants bind to and neutralize ('scavenge') free radicals, thereby transforming them into non-toxic compounds and blocking their genotoxic and carcinogenic effects. This class of agents includes the vitamins C and E, the carotenoids, and selenium. Organic antioxidants are found in high concentrations in fruits, seeds and vegetables. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C275

ALT_DEFINITION

Agent used to stabilize a system against oxidative degradation. (Adapted from Medicinescomplete)

A substance that protects cells from the damage caused by free radicals (unstable molecules made by the process of oxidation during normal metabolism). Free radicals may play a part in cancer, heart disease, stroke, and other diseases of aging. Antioxidants include beta-carotene, lycopene, vitamins A, C, and E, and other natural and manufactured substances.

CHEBI_ID

CHEBI:22586

code

C275

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133805

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176676

Contributing_Source

FDA

DEFINITION

A group of organic or inorganic substances capable of preventing the genotoxic and carcinogenic effects of free-radical compounds. Antioxidants bind to and neutralize ('scavenge') free radicals, thereby transforming them into non-toxic compounds and blocking their genotoxic and carcinogenic effects. This class of agents includes the vitamins C and E, the carotenoids, and selenium. Organic antioxidants are found in high concentrations in fruits, seeds and vegetables. (NCI04)

FULL_SYN

antioxidant

Antioxidant

label

Antioxidant

Legacy Concept Name

Antioxidant

Preferred_Name

Antioxidant

prefixIRI

Thesaurus:C275

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0003402

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26170

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http://purl.bioontology.org/ontology/CSP/2164-9171 CRISP LOOM
http://purl.jp/bio/4/id/200906098768305680 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 ENM LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 UBERON LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 PROCO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 CLO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 GCBO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 FOVT LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 OCMR LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 RBO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 PCL LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 BAO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 NIFDYS LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 NBO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 FB-CV LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 CHIRO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 ECAO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 PECO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 FYPO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 ECTO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 MCO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 MAXO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 ZP LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 AISM LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 NMDCO LOOM
http://purl.obolibrary.org/obo/CHEBI_22586 OBA LOOM
http://www.pepathway.org/peo/1.2#antioxidant PE-O LOOM
http://scai.fraunhofer.de/HuPSON#SCAIVPH_00001337 HUPSON LOOM
http://www.projecthalo.com/aura#Antioxidant AURA LOOM
http://purl.obolibrary.org/obo/XCO_0000271 XCO LOOM
http://purl.jp/bio/4/id/kb0000000413 IOBC LOOM
http://chem.deri.ie/granatum#Antioxidant CANCO LOOM
http://purl.obolibrary.org/obo/NCIT_C275 BERO LOOM
http://purl.obolibrary.org/obo/LFID_0006541 LSFO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00544 MIO LOOM