National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

ALK Tyrosine Kinase Receptor
Synonyms

Anaplastic Lymphoma Kinase

CD246 Antigen

EC 2.7.10.1

ALK Tyrosine Kinase Receptor

ALK

Definitions

ALK tyrosine kinase receptor (1620 aa, ~176 kDa) is encoded by the human ALK gene. This protein is involved in ligand binding, tyrosine phosphorylation and signal transduction.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C27032

code

C27032

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

ALK tyrosine kinase receptor (1620 aa, ~176 kDa) is encoded by the human ALK gene. This protein is involved in ligand binding, tyrosine phosphorylation and signal transduction.

DesignNote

ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. (LocusLink)

Display_Name

ALK Tyrosine Kinase Receptor

FULL_SYN

Anaplastic Lymphoma Kinase

CD246 Antigen

EC 2.7.10.1

ALK Tyrosine Kinase Receptor

ALK

label

ALK Tyrosine Kinase Receptor

Legacy Concept Name

Anaplastic_Lymphoma_Kinase

OMIM_Number

105590

Preferred_Name

ALK Tyrosine Kinase Receptor

prefixIRI

Thesaurus:C27032

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Receptor

Swiss_Prot

Q9UM73

UMLS_CUI

C1663627

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C150444

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17660

Delete Subject Author Type Created
No notes to display