Preferred Name | Growth/Differentiation Factor 5 | |
Synonyms |
Lipopolysaccharide-Associated Protein 4 GDF5 Protein Growth/Differentiation Factor 5 Cartilage-Derived Morphogenetic Protein 1 Growth Differentiation Factor 5 LPS-Associated Protein 4 Cartilage-Derived Morphogenetic Protein-1 Bone Morphogenetic Protein 14 BMP-14 CDMP-1 GDF-5 GDF5 LAP-4 |
|
Definitions |
Growth/differentiation factor 5 (501 aa, ~55 kDa) is encoded by the human GDF5 gene. This protein is involved in skeletal development. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26322 |
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code |
C26322 |
|
DEFINITION |
Growth/differentiation factor 5 (501 aa, ~55 kDa) is encoded by the human GDF5 gene. This protein is involved in skeletal development. |
|
DesignNote |
Growth/differentiation factor 5 is predominantly expressed in long bones during human embryonic development. The active growth factor is released from the precursor following proteolytic cleavage at arginine at amino acid position 381 which is the final amino acid in a polybasic proteolytic processing site. (EntrezGene and UniProt) |
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FULL_SYN |
Lipopolysaccharide-Associated Protein 4 GDF5 Protein Growth/Differentiation Factor 5 Cartilage-Derived Morphogenetic Protein 1 Growth Differentiation Factor 5 LPS-Associated Protein 4 Cartilage-Derived Morphogenetic Protein-1 Bone Morphogenetic Protein 14 BMP-14 CDMP-1 GDF-5 GDF5 LAP-4 |
|
label |
Growth/Differentiation Factor 5 |
|
Legacy Concept Name |
Growth_Differentiation_Factor-5 |
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OMIM_Number |
601146 |
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Preferred_Name |
Growth/Differentiation Factor 5 |
|
prefixIRI |
Thesaurus:C26322 |
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Semantic_Type |
Amino Acid, Peptide, or Protein Biologically Active Substance |
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Swiss_Prot |
P43026 |
|
UMLS_CUI |
C2003595 |
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subClassOf |