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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Interferon Alpha-2 | |
| Synonyms |
IFNA2 Protein Interferon Alpha-A Alpha-2a Interferon Interferon Alpha-2 IFN-Alpha-2 Interferon Alpha 2 Interferon Alpha 2b Interferon Alpha 2a Alpha-2-Interferon Interferon Alpha A IFN-AlphaA IFNA2 LeIF A |
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| Definitions |
Interferon alpha-2 (188 aa, ~22 kDa) is encoded by the human IFNA2 gene. This protein is involved in antiviral defense, cell-cell signaling, and immune activation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26318 |
|
| code |
C26318
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|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
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| Contributing_Source |
CTRP
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| DEFINITION |
Interferon alpha-2 (188 aa, ~22 kDa) is encoded by the human IFNA2 gene. This protein is involved in antiviral defense, cell-cell signaling, and immune activation.
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|
| DesignNote |
There are 3 forms of interferon alpha-2. Alpha-2a is the canonical form. Alpha-2b is the result of a SNP that has the variant amino acid Lys46Arg. Alpha-2c has the amino acid variation Lys46Arg, and an additional variation His57Arg. (UniProt)
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| Display_Name |
Interferon Alpha-2
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|
| FULL_SYN |
IFNA2 Protein Interferon Alpha-A Alpha-2a Interferon Interferon Alpha-2 IFN-Alpha-2 Interferon Alpha 2 Interferon Alpha 2b Interferon Alpha 2a Alpha-2-Interferon Interferon Alpha A IFN-AlphaA IFNA2 LeIF A
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|
| label |
Interferon Alpha-2
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|
| Legacy Concept Name |
Interferon_Alpha-2
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| OMIM_Number |
147562
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|
| Preferred_Name |
Interferon Alpha-2
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|
| prefixIRI |
Thesaurus:C26318
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| Semantic_Type |
Amino Acid, Peptide, or Protein Immunologic Factor
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| Swiss_Prot |
P01563
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| UMLS_CUI |
C0535872
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| subClassOf |
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