National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ephrin Type-A Receptor 2

Synonyms

Ephrin Receptor Epha2

Tyrosine-Protein Kinase Receptor ECK

Epithelial Cell Kinase

Ephrin Type-A Receptor 2

EC 2.7.1.112

Epithelial Cell Receptor Protein-Tyrosine Kinase

Epithelial Cell Receptor Protein Tyrosine Kinase

EC 2.7.10.1

EPHA2

Definitions

Ephrin type-A receptor 2 (976 aa, ~108 kDa) is encoded by the human EPHA2 gene. This protein plays a role in ephrin-A binding, cell-cell signaling and signaling pathway regulation.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26156

code

C26156

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Ephrin type-A receptor 2 (976 aa, ~108 kDa) is encoded by the human EPHA2 gene. This protein plays a role in ephrin-A binding, cell-cell signaling and signaling pathway regulation.

DesignNote

The signaling pathways downstream of ephrin receptors are referred to as forward signaling while the signaling pathways downstream of the ephrin ligands are referred to as reverse signaling. (UniProt)

Display_Name

Ephrin Type-A Receptor 2

FULL_SYN

Ephrin Receptor Epha2

Tyrosine-Protein Kinase Receptor ECK

Epithelial Cell Kinase

Ephrin Type-A Receptor 2

EC 2.7.1.112

Epithelial Cell Receptor Protein-Tyrosine Kinase

Epithelial Cell Receptor Protein Tyrosine Kinase

EC 2.7.10.1

EPHA2

label

Ephrin Type-A Receptor 2

Legacy Concept Name

Ephrin_Receptor-Epha2

OMIM_Number

176946

Preferred_Name

Ephrin Type-A Receptor 2

prefixIRI

Thesaurus:C26156

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Receptor

Swiss_Prot

P29317

UMLS_CUI

C1333410

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17660

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