National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

D(1A) Dopamine Receptor
Synonyms

Dopamine D1 Receptor

D(1A) Dopamine Receptor

Dopamine Receptor D1

Dopamine Receptor D1A

DRD1

Definitions

D(1A) dopamine receptor (446 aa, ~49 kDa) is encoded by the human DRD1 gene. This protein is involved in neurotransmitter-dependent G protein-coupled receptor signaling.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26120

code

C26120

DEFINITION

D(1A) dopamine receptor (446 aa, ~49 kDa) is encoded by the human DRD1 gene. This protein is involved in neurotransmitter-dependent G protein-coupled receptor signaling.

DesignNote

Dopamine Receptor D1, encoded by the human DRD1 gene, is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. It regulates neuronal growth and development, mediates some behavioral responses, and modulates dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.

FULL_SYN

Dopamine D1 Receptor

D(1A) Dopamine Receptor

Dopamine Receptor D1

Dopamine Receptor D1A

DRD1

label

D(1A) Dopamine Receptor

Legacy Concept Name

Dopamine_Receptor-D1

OMIM_Number

126449

Preferred_Name

D(1A) Dopamine Receptor

prefixIRI

Thesaurus:C26120

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

Swiss_Prot

P21728

UMLS_CUI

C3711530

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17066

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