National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Interleukin-2 Gene
Synonyms

Interleukin-2 Gene

IL-2 Gene
Definitions

The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. (NCI04)
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2549
code

C2549
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784
Contributing_Source

CTRP
DEFINITION

The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression. (NCI04)
Display_Name

Interleukin-2 Gene
FULL_SYN

Interleukin-2 Gene

IL-2 Gene
label

Interleukin-2 Gene
Legacy Concept Name

Interleukin-2_Gene
NCI_Drug_Dictionary_ID

38045
NCI_META_CUI

CL448417
PDQ_Closed_Trial_Search_ID

38045
PDQ_Open_Trial_Search_ID

38045
Preferred_Name

Interleukin-2 Gene
prefixIRI

Thesaurus:C2549
Semantic_Type

Pharmacologic Substance

Gene or Genome
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2178
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