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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Thyroglobulin | |
| Synonyms |
Thyroglobulin thyroglobulin THYROGLOBULIN Thyroid Thyroglobulin TG Tg |
|
| Definitions |
Thyroglobulin (2768 aa, ~305 kDa) is encoded by the human TG gene. This protein is involved in thyroid hormone synthesis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2304 |
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| ALT_DEFINITION |
The form that thyroid hormone takes when stored in the cells of the thyroid. If the thyroid has been removed, thyroglobulin should not show up on a blood test. Doctors measure thyroglobulin level in blood to detect thyroid cancer cells that remain in the body after treatment. An antigen encoded by the TG gene that regulates thyroid hormone synthesis. It can be considered as an autoantigen and is commonly associated with autoimmune thyroid diseases.
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| code |
C2304
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
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| Contributing_Source |
CDISC CTRP
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| DEFINITION |
Thyroglobulin (2768 aa, ~305 kDa) is encoded by the human TG gene. This protein is involved in thyroid hormone synthesis.
|
|
| DesignNote |
Thyroglobulin is the precursor for both the free and iodinated forms of thyroxine (T4) and triiodothyronine (T3).
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|
| Display_Name |
Thyroglobulin
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| FULL_SYN |
Thyroglobulin thyroglobulin THYROGLOBULIN Thyroid Thyroglobulin TG Tg
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|
| label |
Thyroglobulin
|
|
| Legacy Concept Name |
Thyroglobulin
|
|
| OMIM_Number |
188450
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|
| Preferred_Name |
Thyroglobulin
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|
| prefixIRI |
Thesaurus:C2304
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| Semantic_Type |
Amino Acid, Peptide, or Protein Hormone
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| Swiss_Prot |
P01266
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| UMLS_CUI |
C0040123
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| subClassOf |
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