National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Amidophosphoribosyltransferase Inhibitor

Synonyms

Amidophosphoribosyltransferase Inhibitor

Definitions

Any substance that inhibits amidophosphoribosyltransferase, an enzyme that catalyzes the commiting step on de novo purine synthesis. Inhibition of amidophosphoribosyltransferase inhibits DNA synthesis and results in cell cycle arrest.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2254

code

C2254

DEFINITION

Any substance that inhibits amidophosphoribosyltransferase, an enzyme that catalyzes the commiting step on de novo purine synthesis. Inhibition of amidophosphoribosyltransferase inhibits DNA synthesis and results in cell cycle arrest.

FULL_SYN

Amidophosphoribosyltransferase Inhibitor

label

Amidophosphoribosyltransferase Inhibitor

Legacy Concept Name

Amidophosphoribosyltransferase_Inhibitor

Preferred_Name

Amidophosphoribosyltransferase Inhibitor

prefixIRI

Thesaurus:C2254

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C1515953

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C471

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