National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Transaminase

Synonyms

Transaminase

Aminotransferase

EC 2.6.1

Definitions

Transaminases are a sub-subclass of mostly pyridoxal phosphate-dependent transferase enzymes that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Mediating conversion of major intermediate metabolites and reversible transamination, Transaminases are often involved in cellular nitrogen metabolism, amino acid metabolism, gluconeogenesis and in the urea and tricarboxylic acid cycles.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21489

code

C21489

DEFINITION

Transaminases are a sub-subclass of mostly pyridoxal phosphate-dependent transferase enzymes that catalyze the transfer of an amino group from a donor (generally an amino acid) to an acceptor (generally a 2-keto acid). Mediating conversion of major intermediate metabolites and reversible transamination, Transaminases are often involved in cellular nitrogen metabolism, amino acid metabolism, gluconeogenesis and in the urea and tricarboxylic acid cycles.

FULL_SYN

Transaminase

Aminotransferase

EC 2.6.1

label

Transaminase

Legacy Concept Name

Transaminase

Preferred_Name

Transaminase

prefixIRI

Thesaurus:C21489

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

UMLS_CUI

C0002594

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17210

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