National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Immunoadjuvant
Synonyms

Immunoadjuvant

Adjuvants, Immunologic

immune adjuvant

Immunologic Adjuvant

Immunologic Adjuvants

immunological adjuvant

Definitions

Adjuvants are mostly pharmacological agents of drug or biological origin used to modify the antigenicity of immunization components, i.e., to stimulate, potentiate, or depress the immune response or to inhibit or enhance specific subclasses of immunocytes. Adjuvants augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. Classical agents (Freund's adjuvant, BCG, Corynebacterium parvum) contain bacterial antigens. Some adjuvants are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a variety of antigens, or antigen-specific, affecting a restricted type of immune response to a narrow group of antigens. Since adjuvants enhance the body's immune response, they can be considered a type of immune modulator.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C210

ALT_DEFINITION

A drug that stimulates the immune system to respond to disease.

CHEBI_ID

CHEBI:50847

code

C210

DEFINITION

Adjuvants are mostly pharmacological agents of drug or biological origin used to modify the antigenicity of immunization components, i.e., to stimulate, potentiate, or depress the immune response or to inhibit or enhance specific subclasses of immunocytes. Adjuvants augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. Classical agents (Freund's adjuvant, BCG, Corynebacterium parvum) contain bacterial antigens. Some adjuvants are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a variety of antigens, or antigen-specific, affecting a restricted type of immune response to a narrow group of antigens. Since adjuvants enhance the body's immune response, they can be considered a type of immune modulator.

FULL_SYN

Immunoadjuvant

Adjuvants, Immunologic

immune adjuvant

Immunologic Adjuvant

Immunologic Adjuvants

immunological adjuvant

label

Immunoadjuvant

Legacy Concept Name

Immunoadjuvant

Preferred_Name

Immunoadjuvant

prefixIRI

Thesaurus:C210

Semantic_Type

Chemical Viewed Functionally

UMLS_CUI

C0001551

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2140

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C308

Delete Subject Author Type Created
No notes to display