Preferred Name |
Transcription Coregulator Gene |
|
Synonyms |
Transcription Coactivator/Corepressor Gene Transcriptional Coregulator Gene Transcription Coregulator Gene |
|
Definitions |
RNA polymerase II transcription of Class II genes involves the TFIID transcription complex comprised of general factors, including TBP, TFIIA, TFIIB, TFIIE, TFIIF, TFIIG/J, and TFIIH, as well as gene-specific factors that include TAFs, which interact with regulatory protein activation domains to enhance transcription. A second group of cofactors includes PC1, PC2, and PC3, which have a strong positive influence on transcription. A third group of factors suppress transcription. The combined action of general and gene-specific regulators encoded by transcription coactivator genes determines appropriate gene expression. (NCI) |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20710 |
|
code |
C20710 |
|
DEFINITION |
RNA polymerase II transcription of Class II genes involves the TFIID transcription complex comprised of general factors, including TBP, TFIIA, TFIIB, TFIIE, TFIIF, TFIIG/J, and TFIIH, as well as gene-specific factors that include TAFs, which interact with regulatory protein activation domains to enhance transcription. A second group of cofactors includes PC1, PC2, and PC3, which have a strong positive influence on transcription. A third group of factors suppress transcription. The combined action of general and gene-specific regulators encoded by transcription coactivator genes determines appropriate gene expression. (NCI) |
|
FULL_SYN |
Transcription Coactivator/Corepressor Gene Transcriptional Coregulator Gene Transcription Coregulator Gene |
|
label |
Transcription Coregulator Gene |
|
Legacy Concept Name |
Transcription_Coregulator_Gene |
|
Preferred_Name |
Transcription Coregulator Gene |
|
prefixIRI |
Thesaurus:C20710 |
|
Semantic_Type |
Gene or Genome |
|
UMLS_CUI |
C1336778 |
|
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/NCIT_C20710 | BERO | LOOM |