Preferred Name | Granulocyte-Macrophage Colony-Stimulating Factor | |
Synonyms |
Colony Stimulating Factor, Granulocyte-Macrophage Colony Stimulating Factor 2 Granulocyte Macrophage Colony Stimulating Factor Granulocyte-Macrophage Colony Stimulating Factor granulocyte-macrophage colony-stimulating factor Granulocyte-Macrophage Colony-Stimulating Factor Colony-Stimulating Factor Colony-Stimulating Factor 2 Granulocyte Macrophage Colony-Stimulating Factor CSF CSF2 GM CSF GM-CSF GMCSF |
|
Definitions |
Granulocyte-macrophage colony-stimulating factor (144 aa, ~16 kDa) is encoded by the human CSF2 gene. This protein plays a role in the positive regulation of the growth and differentiation of cells in the granulocyte, macrophage, eosinophil and erythrocyte lineages. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20545 |
|
ALT_DEFINITION |
A substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that become platelets. It is a cytokine that is a type of hematopoietic (blood-forming) agent. |
|
code |
C20545 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
Contributing_Source |
CTRP |
|
DEFINITION |
Granulocyte-macrophage colony-stimulating factor (144 aa, ~16 kDa) is encoded by the human CSF2 gene. This protein plays a role in the positive regulation of the growth and differentiation of cells in the granulocyte, macrophage, eosinophil and erythrocyte lineages. |
|
DesignNote |
The active form of the protein is found extracellularly as a homodimer. |
|
Display_Name |
Granulocyte-Macrophage Colony-Stimulating Factor |
|
FULL_SYN |
Colony Stimulating Factor, Granulocyte-Macrophage Colony Stimulating Factor 2 Granulocyte Macrophage Colony Stimulating Factor Granulocyte-Macrophage Colony Stimulating Factor granulocyte-macrophage colony-stimulating factor Granulocyte-Macrophage Colony-Stimulating Factor Colony-Stimulating Factor Colony-Stimulating Factor 2 Granulocyte Macrophage Colony-Stimulating Factor CSF CSF2 GM CSF GM-CSF GMCSF |
|
label |
Granulocyte-Macrophage Colony-Stimulating Factor |
|
Legacy Concept Name |
Colony_Stimulating_Factor-2 |
|
NCI_META_CUI |
CL1374956 |
|
OMIM_Number |
138960 |
|
Preferred_Name |
Granulocyte-Macrophage Colony-Stimulating Factor |
|
prefixIRI |
Thesaurus:C20545 |
|
Semantic_Type |
Amino Acid, Peptide, or Protein Immunologic Factor |
|
Swiss_Prot |
P04141 |
|
subClassOf |