National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Granulocyte-Macrophage Colony-Stimulating Factor
Synonyms

Colony Stimulating Factor, Granulocyte-Macrophage

Colony Stimulating Factor 2

Granulocyte Macrophage Colony Stimulating Factor

Granulocyte-Macrophage Colony Stimulating Factor

granulocyte-macrophage colony-stimulating factor

Granulocyte-Macrophage Colony-Stimulating Factor

Colony-Stimulating Factor

Colony-Stimulating Factor 2

Granulocyte Macrophage Colony-Stimulating Factor

CSF

CSF2

GM CSF

GM-CSF

GMCSF

Definitions

Granulocyte-macrophage colony-stimulating factor (144 aa, ~16 kDa) is encoded by the human CSF2 gene. This protein plays a role in the positive regulation of the growth and differentiation of cells in the granulocyte, macrophage, eosinophil and erythrocyte lineages.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20545

ALT_DEFINITION

A substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that become platelets. It is a cytokine that is a type of hematopoietic (blood-forming) agent.

code

C20545

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Granulocyte-macrophage colony-stimulating factor (144 aa, ~16 kDa) is encoded by the human CSF2 gene. This protein plays a role in the positive regulation of the growth and differentiation of cells in the granulocyte, macrophage, eosinophil and erythrocyte lineages.

DesignNote

The active form of the protein is found extracellularly as a homodimer.

Display_Name

Granulocyte-Macrophage Colony-Stimulating Factor

FULL_SYN

Colony Stimulating Factor, Granulocyte-Macrophage

Colony Stimulating Factor 2

Granulocyte Macrophage Colony Stimulating Factor

Granulocyte-Macrophage Colony Stimulating Factor

granulocyte-macrophage colony-stimulating factor

Granulocyte-Macrophage Colony-Stimulating Factor

Colony-Stimulating Factor

Colony-Stimulating Factor 2

Granulocyte Macrophage Colony-Stimulating Factor

CSF

CSF2

GM CSF

GM-CSF

GMCSF

label

Granulocyte-Macrophage Colony-Stimulating Factor

Legacy Concept Name

Colony_Stimulating_Factor-2

NCI_META_CUI

CL1374956

OMIM_Number

138960

Preferred_Name

Granulocyte-Macrophage Colony-Stimulating Factor

prefixIRI

Thesaurus:C20545

Semantic_Type

Amino Acid, Peptide, or Protein

Immunologic Factor

Swiss_Prot

P04141

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20586

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