loading...| Preferred Name |
Tumor Necrosis Factor |
|
| Synonyms |
Tumor Necrosis Factor-alpha (macrophage-derived) Tumor Necrosis Factor-Alpha Tumor Necrosis Factor Tumor Necrosis Factor Alpha Tumor Necrosis Factor Ligand Superfamily Member 2 TNF TNF Alpha TNF-A TNF-Alpha TNFA |
|
| Definitions |
Tumor necrosis factor (233 aa, ~26 kDa) is encoded by the human TNF gene. This protein is involved in the induction of cytokine expression, the stimulation of cell proliferation and the positive regulation of cell differentiation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20535 |
|
| code |
C20535 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
Tumor necrosis factor (233 aa, ~26 kDa) is encoded by the human TNF gene. This protein is involved in the induction of cytokine expression, the stimulation of cell proliferation and the positive regulation of cell differentiation. |
|
| DesignNote |
Tumor necrosis factor (TNF) is a serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes which has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. |
|
| Display_Name |
Tumor Necrosis Factor |
|
| FULL_SYN |
Tumor Necrosis Factor-alpha (macrophage-derived) Tumor Necrosis Factor-Alpha Tumor Necrosis Factor Tumor Necrosis Factor Alpha Tumor Necrosis Factor Ligand Superfamily Member 2 TNF TNF Alpha TNF-A TNF-Alpha TNFA |
|
| label |
Tumor Necrosis Factor |
|
| Legacy Concept Name |
Tumor_Necrosis_Factor-Alpha |
|
| OMIM_Number |
191160 |
|
| Preferred_Name |
Tumor Necrosis Factor |
|
| prefixIRI |
Thesaurus:C20535 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Immunologic Factor |
|
| Swiss_Prot |
P01375 |
|
| UMLS_CUI |
C1448177 |
|
| subClassOf |