National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Interleukin-11

Synonyms

Adipogenesis Inhibitory Factor

interleukin-11

Interleukin 11

Interleukin-11

AGIF

IL-11

IL11

Definitions

Interleukin-11 (199 aa, ~21 kDa) is encoded by the human IL11 gene. This protein is involved in the proliferation of hematopoietic cells and the induction of platelet production.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20513

ALT_DEFINITION

One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-11 is made by support cells in the bone marrow. It causes the growth of several types of blood cells. Oprelvekin (interleukin-11 made in the laboratory) is used as a biological response modifier to increase the number of platelets, especially in patients receiving chemotherapy for cancer. Interleukin-11 is a type of cytokine.

code

C20513

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

Contributing_Source

CTRP

DEFINITION

Interleukin-11 (199 aa, ~21 kDa) is encoded by the human IL11 gene. This protein is involved in the proliferation of hematopoietic cells and the induction of platelet production.

Display_Name

Interleukin-11

FULL_SYN

Adipogenesis Inhibitory Factor

interleukin-11

Interleukin 11

Interleukin-11

AGIF

IL-11

IL11

label

Interleukin-11

Legacy Concept Name

Interleukin-11

OMIM_Number

147681

Preferred_Name

Interleukin-11

prefixIRI

Thesaurus:C20513

Semantic_Type

Amino Acid, Peptide, or Protein

Immunologic Factor

Swiss_Prot

P20809

UMLS_CUI

C0083031

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20497

Delete Subject Author Type Created
No notes to display