loading...| Preferred Name |
Interleukin-8 |
|
| Synonyms |
T-Cell Chemotactic Factor Lymphocyte Derived Neutrophil Activating Peptide Granulocyte Chemotactic Peptide Interleukin 8 Macrophage-Derived Chemotactic Factor Anionic Neutrophil Activating Peptide Lung Giant Cell Carcinoma-Derived Chemotactic Protein Neutrophil-Activating Protein 1 Granulocyte Chemotactic Protein 1 Interleukin 8 C-X-C Motif Chemokine 8 Beta Endothelial Cell-Derived Neutrophil Activating Peptide Beta-Thromboglobulin-Like Protein Monocyte-Derived Neutrophil Chemotactic Factor Leukocyte Adhesion Inhibitor Neutrophil Activation Factor Anionic Neutrophil-Activating Peptide Neutrophil Chemotactic Factor Protein 3-10C Neutrophil-Activating Peptide 1 Monocyte-Derived Neutrophil-Activating Peptide Neutrophil Activation Peptide Interleukin-8 Alveolar Macrophage Chemotactic Factor I CXCL8 GCP-1 GCP-IL-8 IL-8 IL8 MDNCF MONAP NAP-1 |
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| Definitions |
Interleukin-8 (99 aa, ~11 kDa) is encoded by the human CXCL8 gene. This protein is involved in chemotaxis and neutrophil activation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20473 |
|
| code |
C20473 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP |
|
| DEFINITION |
Interleukin-8 (99 aa, ~11 kDa) is encoded by the human CXCL8 gene. This protein is involved in chemotaxis and neutrophil activation. |
|
| DesignNote |
Interleukin-8 is cleaved into the following seven chains: MDNCF-a (GCP/IL-8 protein IV, IL8/NAP1 form I), Interleukin-8 ((Ala-IL-8)77, GCP/IL-8 protein II, IL-8(1-77), IL8/NAP1 form II, MDNCF-b), IL-8(5-77), IL-8(6-77) ((Ser-IL-8)72, GCP/IL-8 protein I, IL8/NAP1 form III, lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF-c, neutrophil-activating factor, NAF), IL-8(7-77) (GCP/IL-8 protein V, IL8/NAP1 form IV), IL-8(8-77) (GCP/IL-8 protein VI, IL8/NAP1 form V), and IL-8(9-77) (GCP/IL-8 protein III; IL8/NAP1 form VI). (UniProt) |
|
| Display_Name |
Interleukin-8 |
|
| FULL_SYN |
T-Cell Chemotactic Factor Lymphocyte Derived Neutrophil Activating Peptide Granulocyte Chemotactic Peptide Interleukin 8 Macrophage-Derived Chemotactic Factor Anionic Neutrophil Activating Peptide Lung Giant Cell Carcinoma-Derived Chemotactic Protein Neutrophil-Activating Protein 1 Granulocyte Chemotactic Protein 1 Interleukin 8 C-X-C Motif Chemokine 8 Beta Endothelial Cell-Derived Neutrophil Activating Peptide Beta-Thromboglobulin-Like Protein Monocyte-Derived Neutrophil Chemotactic Factor Leukocyte Adhesion Inhibitor Neutrophil Activation Factor Anionic Neutrophil-Activating Peptide Neutrophil Chemotactic Factor Protein 3-10C Neutrophil-Activating Peptide 1 Monocyte-Derived Neutrophil-Activating Peptide Neutrophil Activation Peptide Interleukin-8 Alveolar Macrophage Chemotactic Factor I CXCL8 GCP-1 GCP-IL-8 IL-8 IL8 MDNCF MONAP NAP-1 |
|
| label |
Interleukin-8 |
|
| Legacy Concept Name |
Interleukin-8 |
|
| OMIM_Number |
146930 |
|
| Preferred_Name |
Interleukin-8 |
|
| prefixIRI |
Thesaurus:C20473 |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Immunologic Factor |
|
| Swiss_Prot |
P10145 |
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| UMLS_CUI |
C1698756 |
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| subClassOf |