National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Transforming Growth Factor
Synonyms

Transforming Growth Factor

Tumor Growth Factors

TGF

Definitions

Transforming Growth Factors are a family of extracellular signaling peptides involved in cell growth stimulation. Found in hematopoietic tissue, various TGF-beta subtypes stimulate wound healing and may inhibit lymphopoiesis and myelopoiesis. TGF-alpha binds to EGFR and stimulates endothelial cell growth.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20453

code

C20453

DEFINITION

Transforming Growth Factors are a family of extracellular signaling peptides involved in cell growth stimulation. Found in hematopoietic tissue, various TGF-beta subtypes stimulate wound healing and may inhibit lymphopoiesis and myelopoiesis. TGF-alpha binds to EGFR and stimulates endothelial cell growth.

FULL_SYN

Transforming Growth Factor

Tumor Growth Factors

TGF

label

Transforming Growth Factor

Legacy Concept Name

Transforming_Growth_Factor

Preferred_Name

Transforming Growth Factor

prefixIRI

Thesaurus:C20453

Semantic_Type

Amino Acid, Peptide, or Protein

UMLS_CUI

C0040691

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20130

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