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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Coagulation Factor XI | |
| Synonyms |
Plasma Thromboplastin Antecedent EC 3.4.21.27 Coagulation Factor XI F11 FXI Factor XI PTA |
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| Definitions |
Coagulation factor XI (625 aa, ~70 kDa) is encoded by the human F11 gene. This protein is involved in the proteolytic activation of coagulation factor IX. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201572 |
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| code |
C201572
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| DEFINITION |
Coagulation factor XI (625 aa, ~70 kDa) is encoded by the human F11 gene. This protein is involved in the proteolytic activation of coagulation factor IX.
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| DesignNote |
Coagulation factor XI is a single chain zymogen that is cleaved after the arginine at amino acid residue 387 into two chains by activated coagulation factor XII. The active form of factor XI is composed of two heavy and two light chains held together by disulfide bonds.
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| FULL_SYN |
Plasma Thromboplastin Antecedent EC 3.4.21.27 Coagulation Factor XI F11 FXI Factor XI PTA
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|
| label |
Coagulation Factor XI
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| OMIM_Number |
264900
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| Preferred_Name |
Coagulation Factor XI
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| prefixIRI |
Thesaurus:C201572
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| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme
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| Swiss_Prot |
P03951
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| subClassOf |
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