loading...| Preferred Name | Complement Factor I | |
| Synonyms |
C3B/C4B Inactivator Complement Control Protein Factor I EC 3.4.21.45 Complement Factor I Complement Component I CFI |
|
| Definitions |
Complement factor I (583 aa, ~66 kDa) is encoded by the human CFI gene. This protein is involved in proteolytic inactivation of the alpha-chain of C3d and the alpha-chain of C4b, which leads to inhibition of the complement cascade. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C198614 |
|
| code |
C198614 |
|
| DEFINITION |
Complement factor I (583 aa, ~66 kDa) is encoded by the human CFI gene. This protein is involved in proteolytic inactivation of the alpha-chain of C3d and the alpha-chain of C4b, which leads to inhibition of the complement cascade. |
|
| DesignNote |
Complement factor I is synthesized as an inactive preproprotein that is cleaved to produce both heavy and light chains, which are linked by disulfide bonds and form the active heterodimeric glycoprotein. (EntrezGene) |
|
| FULL_SYN |
C3B/C4B Inactivator Complement Control Protein Factor I EC 3.4.21.45 Complement Factor I Complement Component I CFI |
|
| label |
Complement Factor I |
|
| OMIM_Number |
217030 |
|
| Preferred_Name |
Complement Factor I |
|
| prefixIRI |
Thesaurus:C198614 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme |
|
| Swiss_Prot |
P05156 |
|
| UMLS_CUI |
C1529475 |
|
| subClassOf |