Link to this page
National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
Jump to:
| Preferred Name | Histone Deacetylase Inhibitor | |
| Synonyms |
Histone Deacetylase Inhibitor HDAC inhibitor histone deacetylase inhibitor HDAC Agent |
|
| Definitions |
Any substance that inhibits histone deacetylase, an enzyme that catalyzes the removal of acetyl groups from core histones. Inhibition of histone deacetylase can result in hyperacetylation of histones, with an effect on gene expression and cell differentiation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1946 |
|
| ALT_DEFINITION |
A substance that causes a chemical change that stops tumor cells from dividing. HDAC inhibitors are being studied in the treatment of cancer.
|
|
| CHEBI_ID |
CHEBI:61115
|
|
| code |
C1946
|
|
| DEFINITION |
Any substance that inhibits histone deacetylase, an enzyme that catalyzes the removal of acetyl groups from core histones. Inhibition of histone deacetylase can result in hyperacetylation of histones, with an effect on gene expression and cell differentiation.
|
|
| FULL_SYN |
Histone Deacetylase Inhibitor HDAC inhibitor histone deacetylase inhibitor HDAC Agent
|
|
| label |
Histone Deacetylase Inhibitor
|
|
| Legacy Concept Name |
Histone_Deacetylase_Inhibitor
|
|
| Preferred_Name |
Histone Deacetylase Inhibitor
|
|
| prefixIRI |
Thesaurus:C1946
|
|
| Semantic_Type |
Chemical Viewed Functionally
|
|
| UMLS_CUI |
C1512474
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping