National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ataxin-7
Synonyms

Spinocerebellar Ataxia Type 7 Protein

ATXN7

Ataxin 7

Ataxin-7

Definitions

Ataxin-7 (892 aa, ~95 kDa) is encoded by the human ATXN7 gene. This protein is involved in the regulation of histone acetylation and chromatin remodeling.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C192714

code

C192714

DEFINITION

Ataxin-7 (892 aa, ~95 kDa) is encoded by the human ATXN7 gene. This protein is involved in the regulation of histone acetylation and chromatin remodeling.

DesignNote

Ataxin-7 is part of the STAGA (SPT3/TAF9/GCN5) transcriptional co-activator complex, which acetylates histone H3 and possibly H4, and the TBP-free TAF-containing (TFTC) histone acetylation complex, a chromatin-acetylating transcription coactivator with histone acetyltransferase activity. (UniProt and ComplexPortal)

FULL_SYN

Spinocerebellar Ataxia Type 7 Protein

ATXN7

Ataxin 7

Ataxin-7

label

Ataxin-7

NCI_META_CUI

CL1912916

OMIM_Number

607640

Preferred_Name

Ataxin-7

prefixIRI

Thesaurus:C192714

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

O15265

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26199

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